Wellbutrin (Bupropion)

FDA Approved

Overall, the community sentiment towards Wellbutrin is mixed, with many users reporting significant benefits while also experiencing notable side effects. The average rating reflects a balance of positive and negative experiences shared by patients.

Commonly Reported Benefits

  • Many users report improved mood and reduced depression symptoms.
  • A significant number experience increased energy and motivation.
  • Some users find relief from anxiety and improved emotional stability.

Commonly Reported Side Effects

  • Common side effects include anxiety, insomnia, and brain fog.
  • Users frequently report sleep disturbances and gastrointestinal issues.
  • Some experience heightened emotional instability and mood swings.

Overall Takeaway

Users of Wellbutrin often highlight its effectiveness in improving mood and energy levels, with many finding it life-changing for their depression. However, the medication is not without its challenges; side effects such as anxiety, sleep disturbances, and cognitive issues are frequently mentioned. It's important for potential users to weigh these benefits against the possible drawbacks, as experiences can vary widely among individuals.

Effectiveness

Users report improvement

62%

Side Effects

Reported side effects

44%

Would Recommend

To others with same condition

60%

Avg. Duration

Average reported usage duration

N/A

Side Effects Frequency
Percentage of users reporting each side effect
Sentiment Analysis
User sentiment from reviews and feedback
Positive
50%
Neutral / Mixed
20%
Negative
30%

HI

Positive
12/24/2025
I am like a dog in heat on Wellbutrin. I know my husband is TIRED cuz be on that thang sometimes 2-3 times a day 😩😂

HU

Positive
12/24/2025
Increase. And not in some extreme way. It's very subtle and I find myself open to having sex whenever. Such a nice change after years on SSRIs.

AF

Positive
2/2/2026
I have been on Wellbutrin for a few months now as a complement to a low dose Zoloft. I feel great! My anxiety is much more manageable and I haven’t struggled with seasonal depression this winter. My hormonal mood swings are more subtle. I did have a bit of insomnia when adjusting to Wellbutrin and if I take it too late in the day I won’t get a good night’s sleep. I wish I had tried this combo sooner.

MS

Positive
2/2/2026
I started it in November and have not experienced insomnia or headaches. Before I upped the dose a bit I did experience heightened anxiety, which is apparently common when you first start. Wellbutrin is one of the best out there in terms of side effects.

ST

Positive
2/2/2026
I love it. Really no side effects for me. And helped with the depression of course. I have ADHD as well so it may also be helping that (I take adhd meds too).

OT

Negative
2/2/2026
Made me way too ragey personally. Which arguably was the same if not worse than being really fucking depressed. Some sleep issues/jitteriness and a decrease in appetite.

BL

Negative
2/2/2026
Some people have a great experience on it! I did not unfortunately. It made me a zombie, and I didn’t care about anything when I was on it. So while I wasn’t feeling depressed anymore, I also wasn’t feeling joy or happiness either. I felt void of emotion. I’m on Prozac now and respond sooo much better to it!

DH

Negative
2/2/2026
I was on Wellbutrin for a year it made my anxiety turn into irritability, my depression was gone though, sex drive stayed the same, and I unfortunately gained 30 pounds on it over the span of a year despite working out 3-5 times a week and tracking what I ate. As soon as I got off I started dropping weight fast

AP

Positive
12/23/2025
Yes kinda. I usually have a pretty high libido but since Wellbutrin it just gets better. It’s so good I don’t wanna stop.

GI

Positive
2/2/2026
I love it. Gives me energy. Makes me horny (sometimes). I suspect I have pmdd as well and I still get really tearful around my period about small things. I've been on it for probably over a year? My anxiety isn't particularly worse or better.
Frequently Asked Questions about Wellbutrin (Bupropion)

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